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ABSTRACT KEY FIGURE Highlights The DEVELOPMENT AND USE OF GLUCAGON-LIKE PEPTIDE-1 STRUCTURE, DISTRIBUTION, AND PHYSIOLOGICAL FUNCTION OF GLP-1 GLP-1 MODULATES LIPID METABOLISM CLINICAL APPLICATION OF GLP-1 IN LIPID METABOLISM AND ADIPOSE-RELATED DISORDERS GLP-1 AND DUAL AGONISTS CONCLUSIONS NOTES REFERENCES About this article ABSTRACT Glucagon-like peptide-1 (GLP-1) is a 30-amino acid peptide hormone that is mainly expressed in the intestine and hypothalamus
This substantially exceeded both semaglutide (approximately 15%) and tirzepatide (approximately 21%) results from comparable trial durations
It is available in various forms, including oral supplements, injections, and topical products, but injections are often preferred for faster and more noticeable results
69 GladyshevV
Drugs that activate GLP-1 R in a similar manner are collectively designated as GLP-1 RAs [18]
10.1111/jmwh.12220 14 DubalD
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