J Immunotoxicol
Lab and animal studies build on this as well, showing the extract reduces inflammatory signals, boosts a protein important for barrier health (filaggrin), and has anti-itch/antibacterial activity (including against C.acnes, the bacteria linked to breakouts)
You should be careful with DHEA, because in high doses it can turn into androgens or estrogens
Effects depend on the dose, the form, the duration of exposure, and individual genetics
Setting these criteria in writing ahead of time, rather than deciding case by case, also makes it easier to justify protocol decisions during peer review or internal audit
Understanding peptide legality helps navigate these complexities