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DSIP was chemically synthesized using a solid-phase method, with its purity (98.5%) confirmed by HPLC, NMR, and MS data

Low levels ( 2.7 mM) exclude a hyperinsulinemic, nonketotic state (because insulin suppresses ketone production)

The pH during the reaction is low, which may cause chromogenic inhibition

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All of these velocities can be seen in Figure 1 and all of the abbreviations in the Table of Acronyms in the Supplementary materials

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