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Physicochemical characterization included particle size distribution, polydispersity index (PDI), and zeta potential (ZP) analysis by dynamic light scattering (DLS), with measurements performed in triplicate (Table 1)

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Although engineered probiotics have not been applied in the clinical treatment of oral and GI precancerous lesions, their advantages, such as stability, specificity, preference, efficient, and relative safety, may make them a new therapeutic option in the future

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Dietary methionine restriction ameliorated fat accumulation, systemic inflammation, and increased energy metabolism by altering gut microbiota in middle-aged mice administered different fat diets