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These early clinical results reinforce the potential of our approach to go beyond slowing the hair loss process and directly drive hair follicle regeneration, said Christina Weng, Chief Medical Officer of Pelage Pharmaceuticals, in the press release
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Therefore, we found that the enhanced insulinotropic effect of exendin-phe1 in vitro is recapitulated in a mouse model of T2D, suggesting that GLP-1R trafficking plays a role in determining the responses to therapeutic GLP-1R agonists in vivo