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Findings were supported by a recently updated metanalysis of 15 trials involving 898 patients were included in this analysis, GLP-1R agonists were found to have a positive impact on left ventricle diastolic function, hypertrophy, and exercise capacity [90]

However, as demand for these GLP-1 medications skyrocketed, compounded semaglutide emerged as an alternative during drug shortages

Sleep apnea: In two 52-week trials , people with moderate to severe sleep apnea and obesity were treated with tirzepatide or placebo