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Tirzepatide has been approved for use in the management of T2D by the US Food and Drug Administration [13], the European Medicines Agency [14] and the Australian Therapeutic Goods Administration [15]
however, patients taking anticoagulants (such as warfarin, apixaban, or rivaroxaban), antiplatelet agents (including aspirin or clopidogrel), or non-steroidal anti-inflammatory drugs (NSAIDs) have an inherently increased bleeding risk
The mechanism of action involves the sulfur (thiol) groups in glutathione molecules, which actively scavenge reactive oxygen species (ROS) and free radicals within cells
These would include, for example, antacid medications that inhibit the bodys production of stomach acid, anti-cholesterol medications that block the production of cholesterol, and selective serotonin reuptake inhibitors (SSRIs) that block the uptake of serotonin to treat depression
This can lead to a larger amount of the drug in your system, which increases your risk of side effects
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