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In contrast, LCACs are thought to have the potential to activate inflammation, activating the NF-B luciferase reporter gene in RAW 264.7 cells in an acyl chain length- and concentration-dependent manner, as well as the phosphorylation of JNK and ERK [54, 55]

[1] Most patients find that gastrointestinal side effects diminish over time as the body adapts to the medication

When you dont take enough, the medication wont be as effective