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The estimated global count of dementia patients is projected to reach 139 million by 2050 (Figure 2, the neuropathological characteristics of AD include extracellular A(amyloid beta) plaques and intracellular hyperphosphorylated tau (p-) forming neurofibrillary tangles, accompanied by synaptic and neuronal loss ( FIGURE 2 Investigations show clear evidence of microglial inflammation at the brain level among humans with AD, which is been visualized in vivo via PET imaging

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