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Ideal candidates might include those who: Have documented binge eating episodes causing significant distress Meet BMI criteria for weight management medications Have not responded adequately to psychological interventions (such as cognitive behavioural therapy) Do not have contraindications to GLP-1 therapy Understand the off-label nature of this indication UK SmPCs for GLP-1 medications note findings of thyroid C-cell tumours in rodent studies, though the relevance to humans remains uncertain

Heres how typical doses compare: 300600mg/day 6001,200mg/day Doses in this range have been studied for their potential to address metabolic dysfunction, inflammation, and oxidative stress

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ANTIAGEING EFFECT Skin ageing can be extrinsic or intrinsic. UV irradiation results in extrinsic ageing

All the differences still have statistical significance after controlling for age, sex, BMI, smoking, and drinking

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