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Fujii H (1999)

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Intestinal permeability, or leaky gut, is a common trigger in autoimmunity, allowing undigested food particles and toxins to enter the bloodstream, which provokes an immune response and fuels inflammation

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Furthermore, vitamin D enhances mitochondrial function by improving oxidative phosphorylation efficiency, reducing electron leakage, and upregulating antioxidant enzymes, such as superoxide dismutase (SOD) and glutathione peroxidase (GPx)

Physicians should monitor these patients more carefully and adjust therapy as needed