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The major adverse effects of GLP-1RAs are nausea and vomiting, which occur in approximately 70% of participants [13]

Similar findings were reported for glucagon/GLP-1 dual agonists, where increased fatty acid oxidation in white adipose tissue contributes significantly to energy expenditure [32, 33]

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Mistake 2: Confusing units with milligrams A prescription says "0.5 mg weekly." A patient draws to the 50-unit mark thinking 50 equals 0.5

Both substances influence insulin signaling and glucose metabolism, though through different mechanisms

Notably, experimental studies have also shown that AChEI administration enhances the cholinergic tone in cholinergic neurons of the basal forebrain in mice, and that these effects are mediated by the activation of Trk receptors [251]