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Marchiori LLM, Marchiori GM, Carlos P, Benites SL, Mendes MSB, Ciquinato DSA
Any present or past endocrine disease in the family
No major randomized controlled trial has demonstrated superior outcomes or acceptable tolerability for combining these two monotherapies, which is why standard-of-care guidelines recommend dose optimization of a single agent first
Rather than eating three meals plus snacks, many patients shift to one or two substantial meals daily plus light snacks, driven by genuine hunger cues rather than habit or schedule
While originally developed for diabetes management, several GLP-1s are now being prescribed at higher doses to help treat obesity
Chris Hummel, a veterinarian at Lovet Pet Health Care in Phoenix, Arizona, who was not involved in the study, confirmed that several GLP-1 drugs are under investigation in domestic animals
