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Neuroprotective role of GLP-1 analog for retinal ganglion cells via PINK1/parkin-mediated mitophagy in diabetic retinopathy

Download figure Open in new tab Figure 3: Boxplots of GSH (left panel) and GABA+ levels (right panel) in the SM1, Thal, mPFC, and SMA regions for the ASD (green) and TDC (orange) groups

Gastrointestinal adverse events (nausea, diarrhea, constipation) were the most common side effects in Phase 2, consistent with the GLP-1 class

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Additionally, variability in patient genetics and treatment history may have influenced the observed metabolic profiles