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doi: 10.1080/09674845.2020.1784568 8 BuentzelJKlempHGKraetznerRSchulzMDihaziGHStreitFet al

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The STEP 1 extension showed 11.6 percentage points of weight regained within 52 weeks of stopping semaglutide

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Going beyond 0.1 mg wastes product without proportional benefit

In clinical trials, GLP-1 therapies have been shown to 14: Reduce HbA1C (a snapshot of blood sugar over three months) Support weight loss Improve overall metabolic control They are often used when first-line treatments like metformin are not enough, or when weight loss and cardiometabolic risk are key considerations