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The inhibitory effect of glucagon-like peptide-1 (GLP-1) 736 amide on gastric acid secretion in humans depends on an intact vagal innervation
This is because GLP-1 medications appetite-suppressing hormonal effects reverse within weeks of stopping
Lv C, Cheng T, Zhang B, Sun K, Lu K
This compound rapidly elevates localized gastric pH, creating a transient, safe microenvironment that allows the large peptide molecule to absorb directly across the gastric mucosa into the systemic circulation
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