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Attenuation of CD4(+)CD25(+) regulatory T cells in the tumor microenvironment by metformin, a Type 2 diabetes drug

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People on GLP-1 drugs stop wanting filling foods first, so protein crashes harder than carbs or fat in the average patients intake log

The FDA cited three concerns: potential immunogenicity (the peptide could trigger immune reactions), manufacturing impurity risks (synthetic peptides can contain truncated sequences and other contaminants), and a lack of human safety data sufficient to evaluate risk