The effect on stroke is remarkable (and was significant in the trials of both semaglutide and dulaglutide), amounting to an 18% risk reduction, also because the other class of new antidiabetic agents with cardiovascular benefits, the SGLT2-inhibitors, show no a similar effect on stroke (but do have a significant effect on heart failure) [24]
Patients may experience tenderness, slight swelling, or redness at the injection sites, but these effects are temporary and will subside on their own within a day
The American Diabetes Association recommends regular blood pressure monitoring and medication titration to maintain blood pressure targets while avoiding symptomatic hypotension
After week 24, discontinuation due to side effects dropped to just 4.2%
Fever and malaise often accompany abscess formation
Validity of claims-based diagnosis for pancreatic cancer was confirmed in at least three independent databases [19,20,21], whereas validation of kidney disease yielded more modest agreement with clinical diagnosis [22, 23]