PLoS One 7 , e31494, doi: 10.1371/journal.pone.0031494 (2012)
Although CD44 is not involved in paracetamol pharmacokinetics, it is implicated in the inflammatory response to liver injury [43]
Across corticosteroids, acetaminophen, NSAIDs, and opioids, a consistent pattern emerges: Inflammation is suppressed, but tissue repair is impaired Pain signals are blocked, but nervous system sensitivity increases Symptoms are quieted, but root causes remain unaddressed Over time, this creates a widening gap between temporary symptom relief and true physiologic recovery
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doi: 10.3945/ajcn.2007.25700 54