Clinicians may monitor complete blood counts, vitamin B12 levels, methylmalonic acid, homocysteine, potassium, or other markers depending on the situation
The temptation to escalate the dose because nothing is happening yet is exactly the mistake the timeline section is designed to head off the mechanism is cumulative, not dose-chased
The piperidinone also engages in the S 1 pocket, where the fluorine on the upstream side forms a hydrogen bond with Tyr631, while the fluorine on the downstream piperidine makes a hydrophobic contact with Tyr666 and Tyr662
Note: Its important to consult with a healthcare professional to determine if this therapy is right for you, especially if you have underlying health conditions or are taking medications
[PMID: 10703712] PubMed record related to this compound for laboratory literature review
Plus, it can be less aggravating on the skin