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These medications may not be appropriate for individuals who: Are pregnant or planning pregnancy Are breastfeeding Have a history of pancreatitis Have severe gastrointestinal disorders Have certain thyroid conditions Healthcare providers will review medical history and current medications to determine suitability

Re-introducing the offending agent is generally discouraged unless essential in a clinical setting

Hepatology 2010;51:1584-92.ArticlePubMedPMC 64

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However, these regimens have been plagued with long term drug toxicity leading to retarded neutrite growth, mitochondrial dysfunction, and oxidative stress 18