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Interestingly, a recent study has demonstrated that mevalonate (MVA), a metabolite in the cholesterol synthesis pathway, can induce TI via activating the IGF1-R and mTOR pathways and subsequent histone modifications in Mo and M (167) ( Figure 3 )
doi: 10.24425/fmc.2021.138956 55 BadawyAA-B
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These findings suggest that Tirzepatide could offer a broader impact on metabolic health than previously anticipated
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