Another microbial-derived metabolite, Urolithin A, a coumarin, is found in plasma of healthy adults and derived from ellagitannins found in pomegranates, walnuts, and berries and has both protective effects on BBB integrity pre stroke and therapeutic effects post stroke [153]
Apart from the enhanced activity of fibroblasts, which are pivotal in collagen synthesis, tissue repair, and regeneration, there was also noted a potential rise in mast cell activation
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