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(20) Intestinal problems: Because B12 is absorbed in the intestines, any disease that impairs intestinal function can interfere with B12 absorption
Which upregulate genes for fat oxidation (CPT1, ACOX1) and mitochondrial biogenesis (PGC-1)
DNMT3A mutation promotes leukemia development through NAM-NAD metabolic reprogramming
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This includes: People with Pernicious Anemia: An autoimmune condition that prevents the absorption of B12 from the gut
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