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The mechanisms likely involve both the hormonal disruption of rapid fat loss (fat tissue helps regulate oestrogen and testosterone) and the direct effects of GLP-1 receptor activation on dopamine-mediated sexual motivation

However, some patients have reported subjective experiences of irritability, mood swings, or emotional changes whilst taking GLP-1 receptor agonists, including Ozempic

A sharp drop in appetite may unintentionally reduce protein, fiber, and overall nutrient intake

Many patients take their injection before bed to sleep through initial nausea

Once you stop taking it, however, youre likely to gain some of the weight back

10.1002/PCA.2827 24 CiavattiniA.Di GiuseppeJ.StortoniP.MontikN.GiannubiloS