Protects Kidneys & Liver As your body metabolizes fat and toxins during weight loss, hydration helps flush byproducts safely
The appetite decrease is of course part of the intended mechanism, but it can become excessive during aggressive titration, leading to inadequate caloric and protein intake
Pharmacy availability issues: Users frequently report that their local pharmacy doesn't have Wegovy or Mounjaro in stock, requiring calls to multiple pharmacies or weeks-long waits for supply
Regulatory agencies, including the FDA and EMA, have issued warnings about vision loss, stomach problems and risks from unapproved or compounded versions
Caveats and Clinical Context While the oral Wegovy pill is a major advancement, several important factors remain: Side Effects: Like all GLP-1s, the pill carries gastrointestinal side effects (nausea, diarrhea), which can impact adherence
Notably, the compound is stable across a wide pH range and fully soluble in aqueous media, unusual properties for a peptide of this size that are attributed to its high proportion of proline and charged residues