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All models included participants' gender, ages, mothers' ages, fathers' ages, and races as covariates

Formulas outside that range are either less effective or more irritating

While this represents a reasonable duration for clinical trials, it provides limited information about safety with years-long continuous use

Furthermore, enhancing the endometrial metabolic microenvironment and glucose transport may provide a more favorable foundation for early embryonic development and implantation

Challenges and Future Directions of GLP-1 'Central Program' Intervention Current challenge: Individual differences and long-term safety Although GLP-1 injections have shown excellent efficacy in clinical trials, their "central plan" interventions still face challenges: Individual metabolic differences There are significant differences in the response of different patients to GLP-1RA, which are related to factors such as gene polymorphism, gut microbiota composition, and metabolic flexibility

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