In one mouse study, researchers found that the peptide reduced the pain felt by the animals in their paws when placed on a mildly hot plate. The authors explained that this could be because GHK is similar in structure to cimetidine, a histamine H2 receptor antagonist sometimes given to reduce pain in certain digestive conditions.3 10 In rodents, doses as low as 0.5mg/kg were found to be effective in delivering these anti-pain effects.25 In a 70kg human, an equivalent dose would be around 5.6mg, though thats likely higher than necessary: pharmaceutical-grade GHK-Cu normally ranges from 0.5 mg to 2.5mg per injection
1628202-19-6 Appearance Solid Molecular Weight 1419.54 (free acid) Formula C 62 H 98 N 16 O 22 .xC 2 H 4 O 2 Color White to off-white Sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val Sequence Shortening GEPPPGKPADDAGLV Shipping Room temperature in continental US
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[PMID: 2037140] PubMed record related to this compound for laboratory literature review
Choose too much water and higher doses become impractically large volumes
Injections are also a good option for those who might forget periodic supplementation through pills, and for those who have poor digestion or absorption rates