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Epithelial restitution and barrier integrity changes would be expected to manifest as improvements in intestinal permeability assays and endoscopic healing scores, such as Simple Endoscopic Score for Crohns Disease [SES-CD] or Mayo Endoscopic Score ( Animal models have mapped specific target cell types to downstream restitution programs

Annual Report, Novo Nordisk, 2024

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If swollen lymph nodes occur during treatment, a thorough medical evaluation is needed to identify the actual cause

This means those with a BMI of 40 or more, and at least 4 weight-related health conditions outlined by NHS guidelines

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