In addition to maintaining hepatic metabolic homeostasis, AMPK activation has been reported to promote mitochondrial function and suppress endoplasmic reticulum (ER) stress 22
Feroptosis of alveolar macrophages in lung cancer
Immunohistochemistry Formalin-fixed, paraffin-embedded tissue sections (5 m) were used for haematoxylin and eosin staining and immunohistochemical analyses
127,128 Target at subchondral bone The therapeutic targets of most of todays OA research are the articular cartilage itself, it is worthwhile to include the search of novel targets in the subchondral bone, which markedly becomes thicker and disrupted the mechanical stability in OA joints
(FEBS Lett 1988, J Clin Invest 1993): estimulacin de sntesis de matriz extracelular en fibroblastos humanos
Cancer 85 , 10551063 (2001)