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7A), synapses with narrow synaptic clefts and sharply defined, electron-dense postsynaptic densities (PSDs), and presynaptic terminals containing abundant synaptic vesicles (SVs) clustered near active zones (Fig

The trial, which began in October 2018, was originally designed to test the hypothesis that semaglutide could protect nondiabetic patients with metabolic syndrome, a condition characterized by excess body fat and insulin resistance, from cardiovascular events

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Some studies reported antidepressant effects of GLP-1 agonists, while others suggested increased risk of depression or anxiety