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Mayorga-Ramos, A., et al

Preclinical studies indicate that NNMT knockdown or inhibition can protect against diet-induced weight gain and improve metabolic parameters without reducing food intake [5] [6]

Gene Regulation: Downregulates senescence markers like p16 (INK4a) and p21 (Waf1), delaying cellular aging

PYY (Peptide YY) : PYY is a satiety hormone produced by L cells in the intestines, which, similar to GLP-1, increases in concentration after meals and can reduce food intake, thereby potentially aiding in combating obesity

Supports the reduction of fat tissue

doi: 10.1002/advs.202305563 66 ShaoNCaiKHongYWuLLuoQ