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These cellular stressors activate inflammatory cascades involving Kupffer cells, recruited macrophages, and other immune cells, perpetuating hepatic inflammation through secretion of inflammatory mediators and cellular damage signals [7]

(Second E.) 277307, (Elsevier, 2010)

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245 SIRT3 is localized in the mitochondria but is also localized in the nucleus and translocated to mitochondria upon DNA damage

Taking capsules with a small amount of food is a reasonable practical choice to reduce gastric acid exposure slightly