Therefore, we conducted a systematic evaluation of the effects of SGLT-2i or GLP-1 RAs on MACE and HHF with or without metformin background therapy by combining previous studies
According to Novo Nordisk, the maker of Saxenda and Wegovy, they recommend eating bland, low-fat foods, such as crackers, toast and rice
The most severe risks include promoting the growth of existing cancers, severe hypoglycemia (low blood sugar), and acromegaly (abnormal bone and organ growth)
Why it might be helpful: Weight loss typically improves lipid profiles
CHRIS MASTERJOHN: I think they could be synergistic
These treatments work by: Stimulating insulin release from the pancreas Reducing glucagon secretion (which lowers glucose production in the liver) Slowing gastric emptying, so you feel full longer Acting on brain centers that control your appetite and cravings These effects help reduce appetite and improve blood sugar control, making managing weight safely and effectively easier