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Cell (2016)

The meniscus is a fibrocartilaginous wedge whose extracellular matrix is dominated by type I collagen arranged in circumferential bundles, with smaller amounts of type II collagen at the core

These essential molecules tend to decrease due to poor dietary habits, lifestyle imbalances, and natural aging, which can contribute to various health issues and signs of aging

Second, the reduced expression of hippocampal TrkB receptors is linked to higher p-tau levels

As we age, vascular stiffness increases, and microcirculation declines

Fast-acting peptides show effects within hours, while structural ones need weeks of dosing before changes appear