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Archived from the original on 5 February 2025

Kelly is the principal investigator in the largest clinical trial yet looking at obesity medication and adolescents, thanks to a $16.8 million research grant from the Patient-Centered Outcomes Research Institute

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Type 2 diabetes is caused by insulin-resistance

In general, although with exceptions, activated endothelial cells act as the initial stimulus, causing the subsequent recruitment of leukocytes which release a host of pro-fibrotic cytokines like IL-6 and TGF-1, which act on local fibroblasts to create a fibrogenic environment, causing the transition from inactive into aberrantly activated SMA expressing myofibroblasts ( ACTA2 and THY1 (encoding for SMA and CD90, respectively), also contribute to the progression of fibrosis ( JAK2 , and affects the bone marrow (59)

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