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Many natural alternatives have limited high-quality clinical trial data, particularly regarding long-term outcomes and cardiovascular effects

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Place of GLP-1RAs in the Treatment of Obesity Currently, pharmacotherapy is recommended as an adjunct to lifestyle modification for individuals with a BMI of at least 30 kg/m 2 , or at least 27 kg/m 2 with comorbidity [5, 9]

Slowed digestion : This leads to increased feelings of fullness after meals, helping curb overeating

Early weight loss may occur during the first month, while more substantial changes often become apparent over several months

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