From June to July, prescribing increased sharply (+0.11 percentage points), representing the largest single-month increase observed during the study period
Structural changes such as cardiomyopathy, cardiac hypertrophy, interstitial cardiac fibrosis, endothelial dysfunction, and contractile protein failure can result from elevated oxidative stress in cardiac tissue (Emran et al
Warning signs include: Trembling or shakiness Sweating and palpitations Confusion or difficulty concentrating Dizziness or light-headedness Hunger and irritability Pale skin and weakness In severe cases, hypoglycaemia can progress to loss of consciousness or seizures if left untreated
The most important thing is to keep life in balance, remembering that diet, physical activity, and stress reduction can lead to a healthy and fulfilling life
The reason for this is that the price per dose is generally 3040% less
The SURMOUNT-1 trial in NEJM reported an average weight loss of around 20% over 72 weeks at the highest dose