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Essentially, GLP-1 medications work by slowing gastric emptying, meaning food stays in your stomach longer before moving through your digestive tract
However, bioavailability could not be reliably estimated since the chosen dose level for intravenous administration was too low for the terminal part of the concentration-time curve to be apparent, and the plasma semaglutide exposure levels in this single-dose trial were generally insufficient for a robust estimation of bioavailability