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CrossRef An expert narrative review on the brain-kidney axis in diabetic kidney disease: Mechanisms and therapeutic insights Zongrui Zhang, Rangzi Yi, Shihong Xiong, Yushu Zhang, Xuebin Cao, Wenqi Zhen, Yang Yang, Na Gong Diabetes Research and Clinical Practice.2026
GLP-1 helps regulate blood sugar and appetite
Severe cases may require temporary discontinuation of the GLP-1 medication, intravenous fluid replacement, and assessment of renal function through serum creatinine and electrolyte measurements
This slowing effect is why Mounjaro commonly causes gastrointestinal side effects
Those changes can increase nervous system arousal, raise heart rate, or cause anxiety and restlessness for some people
The weight loss component is particularly significant
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