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It serves as an excellent substrate for testing extracellular matrix (ECM) remodelling, angiogenic upregulation, and the modulation of cellular inflammatory pathways under induced stress
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Grudzien-Nogalska, E
Zuo et al., 2024
Orforglipron (LY3502970), a novel, oral non-peptide glucagon-like peptide-1 receptor agonist: A Phase 1a, blinded, placebo-controlled, randomized, single- and multiple-ascending-dose study in healthy participants
Missing data for the trial product estimand were handled through multiple imputation using the Markov Chain Monte Carlo method, assuming that non-adherent participants would have responded similarly to adherent participants within the same treatment arm
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