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Furthermore, heritability estimates range from 30 to 40% (Girgenti et al., 2021) with genome-wide studies implicating immune-linked loci such as ANKRD55 among others (Stein et al., 2016

Results from evidence syntheses Recent cardiovascular, kidney and HF outcomes trials have been incorporated in updated meta-analyses assessing SGLT2i or GLP-1 RA, both in the overall trial populations and in clinically relevant subgroups

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Hussain S, et al

Adipose tissue produces estrogen through aromatase conversion