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By week 8 to 12, most patients reach a therapeutic dose that produces steady, sustainable weight loss

Continued research and well-designed clinical trials are essential to validate its benefits and ensure its safe application in medical practice

Nutritional approaches tailored to perimenopausal physiology include: Protein optimisation : Moderate protein intake (around 1.01.2 g/kg body weight daily for most women) may help preserve muscle mass and enhance satiety

A molecular census of arcuate hypothalamus and median eminence cell types

Staying well-hydrated helps