Xin L, Mekle R, Fournier M, Baumann PS, Ferrari C, Alameda L, et al
NK: Writing original draft, Writing review & editing
The term describes facial hollowing, looser skin, deeper folds, and a more aged appearance that can become noticeable after substantial weight loss on semaglutide, tirzepatide, or another GLP-1 medication
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Heres why: Gut Microbiome and GLP-1 Production : Your gut microbiome can influence the secretion of GLP-1
GLP-1 receptor agonists have been shown in multiple studies to exert anti-inflammatory effects, including inhibition of monocyte chemotaxis, suppression of macrophage inflammatory responses, and AMPK-mediated downregulation of the NF-B signaling pathway, thereby reducing systemic inflammation (36)