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Someone who is caffeine naive may experience a diuretic effect after a moderate to high caffeine dose, but someone who is used to consuming ~300 mg at a time probably wont

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doi: 10.1016/j.chembiol.2020.03.015 58 LeeJYNamMSonHYHyunKJangSYKimJWet al

High dose folic acid, plus vitamins B6 and B12 added to Adalimumab can worsen psoriasis in patients with low BMIs and in others may cause unanticipated EKG effects

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