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Fission can fragment mitochondria, making them more vulnerable to damage and dysfunction, while promoting the release of pro-apoptotic factors that increase cell death likelihood (50)

Additional information Edited by G Melino Supplemental Information accompanies the paper on the Cell Death Discovery website ( Supplementary information Rights and permissions This work is licensed under a Creative Commons Attribution 4.0 International License

Allodynia This is a painful response to a stimulus that wouldnt normally be considered painful at all, such as a light touch or a cold wind

Amber Vials Lyophilized research materials are packaged in amber glass vials designed to reduce light exposure during storage and laboratory handling

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Keep these separate from water-reconstituted peptides different solvents, different vials