For those exploring peptides for gut health , understanding GI side effects from GLP-1 agonists is particularly relevant, as the mechanisms overlap significantly
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In trials by the New England Journal of Medicine, it was found that participants with overweight or obesity, once weekly semaglutide, plus lifestyle intervention (this is key!) was associated with sustained, clinically relevant reduction in body weight
Meaning we can eat relatively large volumes of naturally satiating foods while painlessly achieving lower calorie intake
Who should avoid semaglutide Semaglutide should not be used by people with: Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Personal or family history of medullary thyroid carcinoma (MTC) Serious allergic reactions to semaglutide Be extra careful if you have pancreatic or kidney problems, diabetic retinopathy, or are pregnant or breastfeeding
Catching and correcting a confirmed deficiency early is generally simpler and less costly than treating the complications that a long-standing deficiency can cause