Solid lines indicate mean protein concentrations smoothed using locally weighted scatterplot smoothing (LOWESS) relative to the index date, and error bars represent standard errors
The generic diabetes drug, metformin, also has some data on diabetes prevention, but so far, no drug has been specifically FDA-approved for the treatment of prediabetes
Methodologically, this layer can be interrogated by integrating hormone-response transcriptional programs, proteomic evidence of downstream effectors, and tissue or uterine-fluid metabolomic signatures capturing steroid-linked transformations
Central sensory-motor crosstalk in the neural gut-brain axis
Cell death is mediated by acyl-CoA synthetase long-chain family member 1 (ACSL1), implicating this isoform in ferroptosis
10.3389/fmed.2021.689042 Front Med