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At lower doses, the margin is wider

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By generating mitochondrial O 2 bursts and promoting advanced glycation end product (AGE)-mediated molecular modifications, ROS impair pancreatic -cell function and induce insulin resistance [340]

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Efficacy and safety of topical delgocitinib in patients with chronic hand eczema: data from a randomized, double-blind, vehicle-controlled phase IIa study