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The Chromeleon Chromatography Data System software package (ThermoFisher Scientific, version 7) quantified catecholamine (DA, NE), L-DOPA and metabolite (DOPAC, HVA) content present in each sample from the respective areas under the HPLC peaks based on defined calibration curves

Antonisamy P, Duraipandiyan V, Aravinthan A, et al

10.1007/s10787-017-0358-8 9 CesarL

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This was because hydroxocobalamin produced by bacteria was changed to cyanocobalamin during purification in activated charcoal columns after separation from the bacterial cultures (because cyanide is naturally present in activated charcoal)

Intramuscular B12 injections bypass the gastrointestinal tract entirely and are recommended for malabsorption conditions or persistent oral intolerance